Intraoperative Radiotherapy for Patients with Carcinoma of the Pancreas

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Studies of intraoperative radiotherapy in carcinoma of the pancreas.

Intraoperative radiotherapy (IORT) involves the administration of therapeutic radiation to malignancies during surgical procedures. IORT permits high dose delivery to tumors with the simultaneous reduction of radiation exposure to normal tissues, which may be directly shielded or operatively mobilized from the treatment volume. IORT has been investigated in various intra-abdominal malignancies,...

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Local recurrence following curative resection of rectal carcinoma is still a major problem. Recurrence rates of more than 30% have been reported in the past, but total mesorectal excision has reduced the incidence to considerably less than 10%. Still, the severe morbidity associated with local recurrence demands additional efforts to guarantee local control. Moreover, it may be hoped that a red...

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We investigated whether intraoperative radiotherapy (IORT) during curative surgery for esophageal carcinoma is useful or not. The cases of 117 patients diagnosed with thoracoabdominal esophageal carcinoma who underwent curative surgery between 1986 and 2007 were reviewed: 72 patients received IORT (IORT group) and 45 did not (non-IORT group). Upper abdominal lymphadenectomy was performed in 115...

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Between 1966 and 1980, 72 patients with operable carcinoma of the lung were treated primarily with radiotherapy because coexisting, nontumor related medical problem, or patient refusal prevented thoracotomy. We compared results obtained in this group with results obtained by thoracotomy in 123 consecutive patients over the age of 70, who were assessed in a similar fashion, but who underwent tho...

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ژورنال

عنوان ژورنال: Annals of Surgery

سال: 1988

ISSN: 0003-4932

DOI: 10.1097/00000658-198806000-00002